If you are searching for a comfort meal that feels like a warm hug from the inside, the Cheesy Chicken Biscuit Casserole Recipe is an absolute winner. This dish blends tender shredded chicken with creamy, cheesy goodness and flaky biscuit pieces, all baked to golden perfection. It’s hearty, satisfying, and full of homestyle flavors that will have everyone asking for seconds. Whether you want a cozy family dinner or a dish that’s easy to whip up when you’re craving something indulgent, this casserole delivers on every level.

Cheesy Chicken Biscuit Casserole Recipe - Recipe Image

Ingredients You’ll Need

Gathering simple, straightforward ingredients is what makes this recipe so approachable. Each component plays a role in creating texture, taste, and that irresistible cheesy flavor that elevates this casserole to something truly special.

2 cups cooked chicken, shredded: Use tender, leftover roast chicken or rotisserie chicken for the best flavor and ease.
1 can (10.75 oz) cream of chicken soup: This creamy base ties all the savory flavors together and keeps the casserole moist.
1 cup sour cream: Adds richness and a slight tang that compliments the cheese beautifully.
1 cup shredded cheddar cheese: Sharp cheddar delivers that melty, gooey texture that makes this dish irresistible.
1/2 cup milk: Helps thin out the mixture just enough to keep it creamy and even.
1/2 teaspoon garlic powder: Infuses a subtle but essential savory depth.
1/4 teaspoon ground black pepper: Balances the richness with a mild kick of spice.
1 can (16 oz) refrigerated biscuits: Flaky and buttery, the biscuits add an amazing texture contrast when cut into pieces.
1/2 cup butter, melted: Poured over the top, this ensures a golden, crispy finish that’s simply mouthwatering.

How to Make Cheesy Chicken Biscuit Casserole Recipe

Step 1: Preheat and Prepare Your Oven

Start by heating the oven to 375°F (190°C). This temperature ensures a nice balance between baking the biscuits all the way through and giving the casserole a delicious golden crust. Preheating is key for an even cook.

Step 2: Mix the Chicken and Creamy Ingredients

In a large bowl, combine the shredded chicken, cream of chicken soup, sour cream, shredded cheddar cheese, milk, garlic powder, and black pepper. Stir everything gently but thoroughly so every bite will be packed with flavor. This mixture is the heart of your casserole, creamy and savory with a perfect cheesy tang.

Step 3: Incorporate the Biscuit Pieces

Take your refrigerated biscuits and cut each one into quarters. Then fold these biscuit pieces carefully into the chicken mixture. This step allows the biscuits to soak up some of the creamy filling while still holding their shape to bring delightful texture to every bite.

Step 4: Assemble in the Baking Dish

Lightly grease a 9×13 inch baking dish, then spoon the entire mixture evenly inside, smoothing the surface just a bit. This is where all your ingredients come together, ready to transform into a bubbling casserole.

Step 5: Add the Melting Butter

Pour the melted butter evenly over the top of the casserole. This step is crucial because it helps create that irresistible golden brown topping that adds so much flavor and crunch.

Step 6: Bake to Perfection

Bake for 35 to 40 minutes until the casserole is bubbly and the top is a gorgeous golden brown. The biscuits should be cooked through and slightly crisp around the edges while the inside remains moist and cheesy.

Step 7: Ready to Serve

Once out of the oven, give your Cheesy Chicken Biscuit Casserole Recipe a few minutes to set before digging in. This rest time lets the flavors meld and the casserole firm up a bit, making serving easier and mess-free.

How to Serve Cheesy Chicken Biscuit Casserole Recipe

Garnishes

A sprinkle of freshly chopped parsley or chives adds a fresh pop of color and a mild herbaceous contrast to the rich, cheesy casserole. For those who like a bit of heat, a few red pepper flakes or a dash of hot sauce on the side can be delightful.

Side Dishes

This casserole pairs beautifully with light, crisp sides such as steamed green beans, a simple mixed green salad with vinaigrette, or roasted vegetables. These sides balance out the richness of the dish and bring brightness to the plate.

Creative Ways to Present

For a fun twist, consider serving this casserole in individual ramekins. It’s perfect for gatherings and makes portion control a breeze. You can also layer some fresh sliced tomatoes on top after baking for added color and freshness.

Make Ahead and Storage

Storing Leftovers

Store leftover casserole in an airtight container in the refrigerator for up to 3 days. This makes for an easy next-day meal that tastes just as comforting as freshly baked.

Freezing

This casserole freezes well either baked or unbaked. If freezing before baking, cover tightly with foil and freeze for up to 2 months. When ready to bake, thaw overnight in the refrigerator and bake as usual. For leftovers, wrap individual portions for quick thaw and reheat convenience.

Reheating

Reheat leftovers in the oven at 350°F until warmed through, about 15–20 minutes. To keep the topping crisp, avoid microwaving if possible. If pressed for time, microwave covered for 2–3 minutes and then finish in a hot oven for a few minutes if needed.

FAQs

Can I use fresh biscuits instead of refrigerated ones?

Absolutely! Fresh biscuit dough works well, just cut it into pieces like instructed. Keep in mind that fresh biscuits might bake a bit faster, so keep an eye on the casserole’s doneness.

Is there a substitute for cream of chicken soup?

You can make your own creamy base by combining chicken broth with heavy cream and a bit of flour for thickening, or use cream of mushroom soup for a different flavor profile.

Can I make this casserole vegetarian?

Yes! Simply swap the chicken for cooked vegetables like mushrooms, zucchini, or spinach, and consider using a vegetarian cream soup or make your own creamy mix.

How do I know when the casserole is done?

The casserole is done when the top is golden brown, the biscuits are cooked through, and the filling is bubbly in the center. A toothpick inserted into the center biscuit pieces should come out clean.

Can I add extra vegetables to this casserole?

Definitely. Diced bell peppers, onions, or frozen peas add flavor and nutrition. Just sauté any raw vegetables before mixing them in to avoid adding excess moisture.

Final Thoughts

There is something so wonderfully comforting and satisfying about the Cheesy Chicken Biscuit Casserole Recipe; it’s like all the best flavors of home-cooked chicken and cheese sprinkled with the flaky magic of biscuits. I highly recommend giving this dish a try on your next cozy night in—it’s bound to become a family favorite in no time!

Cheesy Chicken Biscuit Casserole Recipe

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4.4 from 54 reviews

Author: admin
Total Time: 50-55 minutes
Yield: 6 servings 1x

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Description

A comforting and cheesy chicken biscuit casserole that’s easy to prepare and perfect for a family dinner. Tender shredded chicken is combined with creamy soup, cheddar cheese, and refrigerated biscuits, baked to golden perfection with a buttery topping.

Ingredients

Scale

Chicken Mixture

2 cups cooked chicken, shredded
1 can (10.75 oz) cream of chicken soup
1 cup sour cream
1 cup shredded cheddar cheese
1/2 cup milk
1/2 teaspoon garlic powder
1/4 teaspoon ground black pepper

Biscuit and Topping

1 can (16 oz) refrigerated biscuits
1/2 cup butter, melted

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Instructions

Preheat Oven: Preheat your oven to 375°F (190°C) to prepare for baking the casserole.
Combine Ingredients: In a large bowl, mix the shredded chicken, cream of chicken soup, sour cream, cheddar cheese, milk, garlic powder, and black pepper until well blended.
Add Biscuits: Cut each refrigerated biscuit into quarters, then gently stir them into the chicken mixture to evenly distribute the biscuit pieces.
Transfer to Baking Dish: Spoon the entire mixture into a greased 9×13 inch baking dish, spreading it out evenly for uniform cooking.
Add Butter Topping: Pour the melted butter evenly over the top of the casserole to ensure a rich, golden crust when baked.
Bake: Bake in the preheated oven for 35-40 minutes, or until the casserole is golden brown on top and the biscuits are fully cooked through.
Serve: Serve hot, ideally paired with a side of steamed vegetables or a fresh salad for a complete meal.

Notes

The shredded cooked chicken can be rotisserie chicken for convenience.
Ensure biscuits are mixed gently to avoid breaking them down into dough.
You can substitute cream of chicken soup with cream of mushroom or celery soup for a flavor twist.
For a lower-fat version, use reduced-fat sour cream and cheddar cheese.
Make sure to grease the baking dish well to prevent sticking.

Prep Time: 15 minutes
Cook Time: 35-40 minutes
Category: Casserole
Method: Baking
Cuisine: American